Effective Combination of DTaP and IPV

VACCINE injections in children, DTaP vaccine, which protects against resistance diptheria, tetanus and whooping cough, can be combined with inactivated poliovirus vaccine (IPV) without reducing the effectiveness of, new research shows.


"When given as a booster dose for children aged 4-6 years," senior investigator Dr. Nicola P. Klein told Reuters Health, "a combined vaccine (which is safe and effective) with separate injections of DTaP and IPV."

Klein from The Kaiser Permanente Vaccine Study Center, Oakland, Calif., and colleagues studied over 4200 children who were randomly assigned to receive the combination vaccine DTaP-IPV or DTaP and IPV vaccines are administered separately. In addition, all children also received the measles, mumps and rubella (German measles or three-day measles).

The findings appear in the journal Pediatric Infectious Disease. "Especially the age of 4 to 6 years received more than four times the vaccine during the early arrival, which is often performed on children or at the beginning of kindergarten, and this combination can potentially reduce the number of injections they received during the one-time presence of a single vaccine," Klein said.


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